Title : 17-Beta-estradiol inhibits transforming growth factor-beta signaling and function in breast cancer cells via activation of extracellular signal-regulated kinase through the G protein-coupled receptor 30.

Pub. Date : 2008 Dec

PMID : 18768737






1 Functional Relationships(s)
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1 Silencing of GPR30 in MCF-7 cells completely reduced the ability of 17-beta-estradiol (E2) to inhibit the TGF-beta pathway. Estradiol transforming growth factor beta 1 Homo sapiens