Title : Hofmeister effect and the phase diagram of lysozyme.

Pub. Date : 2008 Jul

PMID : 18763996






3 Functional Relationships(s)
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1 The phase diagrams for lysozyme are calculated for two different precipitant salts, NaCl and NaSCN, using a potential of mean force that takes into account contributions from ion-dispersion forces [M. Bostrom, J. Phys. Sodium Chloride lysozyme Homo sapiens
2 Our results are consistent with a recent perturbation theory calculation (referenced above) in that the phase diagram for lysozyme with NaCl is quite different than for lysozyme with NaSCN for the same molar concentration (0.2M) . Sodium Chloride lysozyme Homo sapiens
3 However, in contrast to the perturbation theory calculation, we find that the lysozyme phase diagram with NaCl has a metastable fluid-fluid coexistence curve and that the metastability gap in the case of NaSCN is much larger than predicted by perturbation theory. Sodium Chloride lysozyme Homo sapiens