Title : Conformational transition of polypeptide chain elongation factor G as determined by electron spin resonance.

Pub. Date : 1976 Nov

PMID : 187579






3 Functional Relationships(s)
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1 It was found that the ESR spectra of EF-G labeled with nitroxide maleimide reagents were modified by the addition of various guanine nucleotides such as GDP, GTP and, to a lesser extent, by Gpp(NH)p and Gpp(CH2)p, indicating that conformational changes accompany the binding of nucleotide ligand. Guanosine Diphosphate G elongation factor mitochondrial 1 Homo sapiens
2 They also indicate that there is a substantial difference in conformation between free EF-G, EF-G-GDP, and EF-G-GTP near the active site essential for interaction with ribosomes. Guanosine Diphosphate G elongation factor mitochondrial 1 Homo sapiens
3 They also indicate that there is a substantial difference in conformation between free EF-G, EF-G-GDP, and EF-G-GTP near the active site essential for interaction with ribosomes. Guanosine Diphosphate G elongation factor mitochondrial 1 Homo sapiens