Title : The ratio of +/-KTS splice variants of the Wilms' tumour suppressor protein WT1 mRNA is determined by an intronic enhancer.

Pub. Date : 2008 Aug

PMID : 18756326






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 One candidate for this trans-factor is the splicing regulator TIA-1, which binds to the pyrimidine-rich enhancer in the primary transcript from the minigene construct and increases the +/-KTS splicing ratio. pyrimidine TIA1 cytotoxic granule associated RNA binding protein Homo sapiens