Title : Actein inhibits the Na+-K+-ATPase and enhances the growth inhibitory effect of digitoxin on human breast cancer cells.

Pub. Date : 2008 Oct 31

PMID : 18755149






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The Na+K+-ATPase is a known target of cardiac glycosides such as digitoxin and ouabain. Digitoxin dynein axonemal heavy chain 8 Homo sapiens
2 Actein"s inhibition of Na+-K+-ATPase activity was less potent than that of digitoxin, but actein potentiated digitoxin"s inhibitory effect on Na+-K+-ATPase activity and MDA-MB-453 breast cancer cell growth. Digitoxin dynein axonemal heavy chain 8 Homo sapiens