Title : Trans-Golgi network and endosome dynamics connect ceramide homeostasis with regulation of the unfolded protein response and TOR signaling in yeast.

Pub. Date : 2008 Nov

PMID : 18753406






1 Functional Relationships(s)
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1 The data link TGN/endosomal dynamics with ceramide homeostasis, UPR activity, and TOR signaling in yeast, and they identify the Sit4 protein phosphatase as a primary conduit through which ceramides link to the UPR. Ceramides type 2A-related serine/threonine-protein phosphatase SIT4 Saccharomyces cerevisiae S288C