Title : Antibodies to cytoplasmic sequences of cloned liver growth hormone (GH) receptors recognize GH receptors associated with tyrosine kinase activity.

Pub. Date : 1991 Sep

PMID : 1874195






5 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 GH stimulates tyrosyl phosphorylation of GH receptors in 3T3-F442A fibroblasts, and highly purified GH receptor preparations exhibit tyrosine kinase activity. cyclo(tyrosyl-tyrosyl) growth hormone receptor Homo sapiens
2 Tyrosyl phosphorylated [125I]human GH-receptor complexes were prepared by immunoprecipitation with phosphotyrosyl-binding antibody; this subpopulation of GH-receptor complexes was recognized by all three antipeptide antibodies. cyclo(tyrosyl-tyrosyl) growth hormone receptor Homo sapiens
3 Tyrosyl phosphorylated [125I]human GH-receptor complexes were prepared by immunoprecipitation with phosphotyrosyl-binding antibody; this subpopulation of GH-receptor complexes was recognized by all three antipeptide antibodies. cyclo(tyrosyl-tyrosyl) growth hormone receptor Homo sapiens
4 The antibodies also recognized similarly isolated tyrosyl phosphorylated GH-receptor complexes, which had been further phosphorylated in solution on tyrosyl residues upon addition of [gamma 32P] ATP. cyclo(tyrosyl-tyrosyl) growth hormone receptor Homo sapiens
5 The antibodies also recognized similarly isolated tyrosyl phosphorylated GH-receptor complexes, which had been further phosphorylated in solution on tyrosyl residues upon addition of [gamma 32P] ATP. cyclo(tyrosyl-tyrosyl) growth hormone receptor Homo sapiens