Title : Identification of prostaglandin E2 receptors mediating perinatal masculinization of adult sex behavior and neuroanatomical correlates.

Pub. Date : 2008 Oct

PMID : 18726914






2 Functional Relationships(s)
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1 In female rats, neonatal treatment with antisense oligonucleotides against EP2 or EP4 but not EP1 or EP3 completely prevented the expression of adult behavior organized by PGE2 exposure. Dinoprostone prostaglandin E receptor 2 Rattus norvegicus
2 The body of evidence suggests that EP2 and EP4 are both necessary and sufficient for PGE2-induced masculinization of sex behavior, whereas EP1 and EP3 provide redundant roles. Dinoprostone prostaglandin E receptor 2 Rattus norvegicus