Pub. Date : 2008 Aug
PMID : 18718058
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | [Regulatory effect of resveratrol on JAK1/STAT3 signal transduction pathway in leukemia]. | Resveratrol | signal transducer and activator of transcription 3 | Mus musculus |
2 | The results indicated that resveratrol could significantly inhibit the JAK1/STAT3 signal transduction pathway, down-regulate expressions of pJAK1 and pSTAT3 and reduce the phosphorylation of JAK1 and STAT3 in a dose-and time-dependent manner. | Resveratrol | signal transducer and activator of transcription 3 | Mus musculus |
3 | The results indicated that resveratrol could significantly inhibit the JAK1/STAT3 signal transduction pathway, down-regulate expressions of pJAK1 and pSTAT3 and reduce the phosphorylation of JAK1 and STAT3 in a dose-and time-dependent manner. | Resveratrol | signal transducer and activator of transcription 3 | Mus musculus |
4 | It is concluded that the resveratrol can regulate signal transduction pathway and reduce the activation of JAK1/STAT3 tyrosine phosphorylation significantly, and therefore resveratrol shows chemotherapeutic potential to leukaemia. | Resveratrol | signal transducer and activator of transcription 3 | Mus musculus |