Title : [Effect of diet overloaded by fats on the enzyme systems of metabolism in rats].

Pub. Date : 2008 Jan-Feb

PMID : 18710030






1 Functional Relationships(s)
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1 A high-fat diet enhanced reactions of biotransformation of amidopyrine, acetanilide, toluene, sulfadimezine, were catalyzed with CYP2E1, CYP3A and enzymes of conjugation, simultaneously it increased the hepatotoxicity of paracetamol. Toluene cytochrome P450, family 2, subfamily e, polypeptide 1 Rattus norvegicus