Title : Role of p38 MAPK and JNK in enhanced cervical cancer cell killing by the combination of arsenic trioxide and ionizing radiation.

Pub. Date : 2008 Sep

PMID : 18695917






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 These results indicate that activation of p38 MAPK is specifically required for translocation of Bax to the mitochondria, and both JNK and p38 MAPK are involved in phosphorylation of Bcl-2 in response to combination treatment with gamma-radiation and As2O3, and that ROS is a critical regulator of p38 MAPK and JNK activations. Arsenic Trioxide BCL2 associated X, apoptosis regulator Homo sapiens