Pub. Date : 2008 Aug-Sep
PMID : 18692596
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | To get further insights into the underlying mechanisms of these effects induced by puerarin, we measured telomerase activity and determined the phosphorylation of serine/threonine protein kinase Akt by using western blot. | puerarin | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | Puerarin significantly increased telomerase activity and phosphorylation of Akt, a downstream effector of phosphoinositide 3-kinase (PI-3K). | puerarin | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | Taken together, the results of the present study indicated that puerarin delayed the onset of EPCs senescence, which may be related to the activation of telomerase through the PI-3K/Akt pathway. | puerarin | AKT serine/threonine kinase 1 | Homo sapiens |