Title : Role of key transmembrane residues in agonist and antagonist actions at the two conformations of the human beta1-adrenoceptor.

Pub. Date : 2008 Nov

PMID : 18687809






1 Functional Relationships(s)
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1 Agonist responses to isoprenaline and CGP 12177 had different sensitivities to beta1-antagonists (e.g., CGP 20712A; log K(D) = -8.65 and -7.26, respectively). Isoproterenol potassium calcium-activated channel subfamily M regulatory beta subunit 1 Homo sapiens