Title : Blueberry polyphenols attenuate kainic acid-induced decrements in cognition and alter inflammatory gene expression in rat hippocampus.

Pub. Date : 2008 Aug

PMID : 18681986






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Kainic acid up-regulated the expression of the inflammatory cytokines IL-1beta and TNF-alpha, the neurotrophic factor IGF-1, and the transcription factor NF-kappaB. Kainic Acid interleukin 1 beta Rattus norvegicus
2 Blueberry and piroxicam supplementations were found to attenuate the kainic acid-induced increase in the expression of IL-1beta, TNF-alpha, and NF-kappaB, while only blueberry was able to augment the increased IGF-1 expression. Kainic Acid interleukin 1 beta Rattus norvegicus