Title : Roles of phosphatidylinositol 3-kinase-Akt and NADPH oxidase in adenosine 5'-triphosphate-sensitive K+ channel function impaired by high glucose in the human artery.

Pub. Date : 2008 Sep

PMID : 18678787

1 Functional Relationships(s)
Compound Name
Protein Name
1 Therefore, it can be concluded that the activation of the phosphatidylinositol 3-kinase-Akt pathway, in combination with the translocation of p47phox, p22phox, and Rac-1, contributes to the superoxide production induced by high glucose, resulting in the impairment of ATP-sensitive K(+) channel function in the human visceral artery. Superoxides Rac family small GTPase 1 Homo sapiens