Title : A protein kinase C activity localized to neuropeptide Y-like neurons mediates ethanol intoxication in Drosophila melanogaster.

Pub. Date : 2008 Sep 22

PMID : 18675322






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In Drosophila melanogaster, NPY-like neuropeptide F (NPF) and its receptor NPFR1 display a parallel function, suggesting that an evolutionarily conserved mechanism may underlie similar behavioral effects of ethanol in diverse organisms. Ethanol neuropeptide F Drosophila melanogaster
2 In Drosophila melanogaster, NPY-like neuropeptide F (NPF) and its receptor NPFR1 display a parallel function, suggesting that an evolutionarily conserved mechanism may underlie similar behavioral effects of ethanol in diverse organisms. Ethanol neuropeptide F Drosophila melanogaster
3 Flies expressing a pseudo-substrate inhibitor of PKC, directed by npf-gal4, displayed decreased ethanol sensitivity. Ethanol neuropeptide F Drosophila melanogaster
4 These findings reveal an uncharacterized role of PKC in NPY/NPF-mediated acute ethanol sensitivity in flies and possibly mammals. Ethanol neuropeptide F Drosophila melanogaster