Title : Interleukin-8 expression is regulated by histone deacetylases through the nuclear factor-kappaB pathway in breast cancer.

Pub. Date : 2008 Nov

PMID : 18669446






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Treatment of MCF-7 cells with the HDAC inhibitor trichostatin A (TSA) led to a strong up-regulation of IL-8 protein and RNA levels in MCF-7 cells. trichostatin A C-X-C motif chemokine ligand 8 Homo sapiens
2 Treatment of MCF-7 cells with the HDAC inhibitor trichostatin A (TSA) led to a strong up-regulation of IL-8 protein and RNA levels in MCF-7 cells. trichostatin A C-X-C motif chemokine ligand 8 Homo sapiens
3 TSA increased binding of acetylated histone 3 to the IL-8 gene promoter. trichostatin A C-X-C motif chemokine ligand 8 Homo sapiens