Title : Requirement of a functional spindle checkpoint for arsenite-induced apoptosis.

Pub. Date : 2008 Oct 15

PMID : 18668508






2 Functional Relationships(s)
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1 The marked correlation between ATO-induced mitotic arrest and apoptosis indicates that the induction of apoptosis by ATO was highly dependent on the functional activation of the spindle checkpoint in cancer cells lacking normal p53 function. Arsenic Trioxide tumor protein p53 Homo sapiens
2 The marked correlation between ATO-induced mitotic arrest and apoptosis indicates that the induction of apoptosis by ATO was highly dependent on the functional activation of the spindle checkpoint in cancer cells lacking normal p53 function. Arsenic Trioxide tumor protein p53 Homo sapiens