Title : Artemisinin inhibits tumor lymphangiogenesis by suppression of vascular endothelial growth factor C.

Pub. Date : 2008

PMID : 18667841






1 Functional Relationships(s)
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1 Furthermore, IL-1beta-induced p38 mitogen-activated protein kinase (MAPK) activation and upregulation of VEGF-C mRNA and protein in LLC cells was also suppressed by artemisinin or by the p38 MAPK inhibitor SB-203580, suggesting that p38 MAPK could serve as a mediator of proinflammatory cytokine-induced VEGF-C expression. SB 203580 interleukin 1 beta Mus musculus