Title : Expression pattern of sonic hedgehog and effect of topical mitomycin C on its expression in human ocular surface neoplasms.

Pub. Date : 2008 May-Jun

PMID : 18661269






4 Functional Relationships(s)
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1 Similar marked expression of Shh was detected in the patient with ocular epithelial dysplasia, and this Shh expression was almost eliminated following topical mitomycin C treatment. Mitomycin sonic hedgehog signaling molecule Homo sapiens
2 Similar marked expression of Shh was detected in the patient with ocular epithelial dysplasia, and this Shh expression was almost eliminated following topical mitomycin C treatment. Mitomycin sonic hedgehog signaling molecule Homo sapiens
3 A cell culture experiment was conducted to examine the effect of mitomycin C on Shh expression in a cultured squamous cell carcinoma cell line. Mitomycin sonic hedgehog signaling molecule Homo sapiens
4 Reduction of Shh expression might be involved in the therapeutic efficacy of topical mitomycin C for ocular surface epithelial neoplasms. Mitomycin sonic hedgehog signaling molecule Homo sapiens