Title : Trypsin can activate the epithelial sodium channel (ENaC) in microdissected mouse distal nephron.

Pub. Date : 2008 Oct

PMID : 18653483






1 Functional Relationships(s)
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1 Whole-cell patch-clamp recordings from principal cells of connecting tubules (CNT) or cortical collecting ducts (CCD) demonstrated that addition of trypsin (20 microg/ml) to the bath solution increased the ENaC-mediated amiloride-sensitive whole cell current (DeltaIAmi) in the majority of cells. Amiloride sodium channel, nonvoltage-gated 1 alpha Mus musculus