Title : Biosensor discovery of thyroxine transport disrupting chemicals.

Pub. Date : 2008 Oct 1

PMID : 18647617






2 Functional Relationships(s)
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1 The TTR assay confirmed the activity of previously identified hydroxylated metabolites of PCBs and PBDEs, halogenated BPA and genistein. Halogenated Diphenyl Ethers transthyretin Homo sapiens
2 These results show that the hydroxylated metabolites of the ubiquitous PBDEs not only target the T4 transport at the TTR level, but also, and to a great extent, at the TBG level where most of the T4 in humans is circulating. Halogenated Diphenyl Ethers transthyretin Homo sapiens