Title : Conformational change of apolipoprotein A-I and HDL formation from model membranes under intracellular acidic conditions.

Pub. Date : 2008 Nov

PMID : 18645209






1 Functional Relationships(s)
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1 Circular dichroism spectral measurements and 8-anilino-1-naphthalenesulfonic acid fluorescence measurements of lipid-free apoA-I ascribed this accelerated rHDL formation to the conformational change of the protein into a rather hydrophobic alpha-helical structure under acidic conditions. 8-anilino-1-naphthalenesulfonic acid apolipoprotein A1 Homo sapiens