Title : Effects of brain natriuretic peptide on renin secretion in normal and hypertonic saline-infused kidney.

Pub. Date : 1991 Jun 6

PMID : 1864303






2 Functional Relationships(s)
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1 The renin secretion rate was attenuated by hypertonic saline infusion (1 mEq NaCl/min) to 87 +/- 31% of control. Sodium Chloride renin Canis lupus familiaris
2 In another group (N = 6), administration of pBNP at a dose of 50 ng/kg per min during hypertonic saline infusion (1 mEq NaCl/min) increased the renin secretion rate to 196 +/- 57%, increased RBF to 160 +/- 13%, increased GFR to 137 +/- 22%, increased V to 221 +/- 29%, and increased UNaV to 218 +/- 29% of the values measured during hypertonic saline infusion. Sodium Chloride renin Canis lupus familiaris