Title : MAPPIT (MAmmalian Protein-Protein Interaction Trap) as a tool to study HIV reverse transcriptase dimerization in intact human cells.

Pub. Date : 2008 Oct

PMID : 18640157






1 Functional Relationships(s)
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1 Treatment with efavirenz resulted in an increased MAPPIT signal, with an EC50 value of 64nM for the p66/p51 interaction, and allowed detection of the p51/p51 homodimerization, confirming the context-dependent asymmetric contribution of both subunits. efavirenz DNA polymerase delta 3, accessory subunit Homo sapiens