Title : Leukotriene B4 receptor 1 expression on dendritic cells is required for the development of Th2 responses and allergen-induced airway hyperresponsiveness.

Pub. Date : 2008 Jul 15

PMID : 18606670






1 Functional Relationships(s)
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1 Compared with recipients of wild-type BMDCs, mice that received BLT1(-/-) BMDCs developed significantly lower AHR to inhaled methacholine, lower goblet cell metaplasia, and eosinophilic infiltration in the airways and decreased levels of Th2 type cytokines in the bronchoalveolar lavage fluid. Methacholine Chloride leukotriene B4 receptor 1 Mus musculus