Title : Targeting the VEGF pathway: antiangiogenic strategies in the treatment of non-small cell lung cancer.

Pub. Date : 2008 Dec

PMID : 18606548






1 Functional Relationships(s)
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1 The finding in study E4599 of a survival benefit for carboplatin-paclitaxel plus bevacizumab - a humanised anti-VEGF monoclonal antibody - over chemotherapy (CT) alone led the U.S. Food and Drug Administration (FDA) to approve the novel combination for first-line treatment of patients with unresectable, locally advanced, recurrent or metastatic non-squamous NSCLC. Carboplatin vascular endothelial growth factor A Homo sapiens