Title : Iron-sulfur cluster biogenesis and human disease.

Pub. Date : 2008 Aug

PMID : 18606475






2 Functional Relationships(s)
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1 Recently, the spectrum of diseases attributable to abnormal Fe-S cluster biogenesis has extended beyond Friedreich ataxia to include a sideroblastic anemia with deficiency of glutaredoxin 5 and a myopathy associated with a deficiency of a Fe-S cluster assembly scaffold protein, ISCU. Iron iron-sulfur cluster assembly enzyme Homo sapiens
2 Recently, the spectrum of diseases attributable to abnormal Fe-S cluster biogenesis has extended beyond Friedreich ataxia to include a sideroblastic anemia with deficiency of glutaredoxin 5 and a myopathy associated with a deficiency of a Fe-S cluster assembly scaffold protein, ISCU. Iron iron-sulfur cluster assembly enzyme Homo sapiens