Pub. Date : 2008 Jul 8
PMID : 18591664
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A390V-SNTA1 expressed with SCN5A, nNOS, and PMCA4b in heterologous cells increased peak and late sodium current compared with WT-SNTA1, and the increase was partially inhibited by NOS blockers. | Sodium | syntrophin alpha 1 | Homo sapiens |
| 2 | Expression of A390V-SNTA1 in cardiac myocytes also increased late sodium current. | Sodium | syntrophin alpha 1 | Homo sapiens |
| 3 | These results establish an SNTA1-based nNOS complex attached to SCN5A as a key regulator of sodium current and suggest that SNTA1 be considered a rare LQTS-susceptibility gene. | Sodium | syntrophin alpha 1 | Homo sapiens |
| 4 | These results establish an SNTA1-based nNOS complex attached to SCN5A as a key regulator of sodium current and suggest that SNTA1 be considered a rare LQTS-susceptibility gene. | Sodium | syntrophin alpha 1 | Homo sapiens |