Title : Analysis of FK506-mediated protection in an organotypic model of spinal cord damage: heat shock protein 70 levels are modulated in microglial cells.

Pub. Date : 2008 Jul 31

PMID : 18577426






1 Functional Relationships(s)
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1 FK506 may exert neuroprotection via inhibition of calcineurin by binding the FKBP12, or by binding other immunophilins such as FKBP52, leading to modulation of heat shock proteins (Hsp) 90 and 70. Tacrolimus FKBP prolyl isomerase 1A Rattus norvegicus