Title : The V433M variant of the CYP4F2 is associated with ischemic stroke in male Swedes beyond its effect on blood pressure.

Pub. Date : 2008 Aug

PMID : 18574070






2 Functional Relationships(s)
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1 Cytochrome (CYP) 4A11 and CYP4F2 are responsible for renal production of 20-hydroxyeicosatetraenoic acid, a vasoconstrictor and natriuretic substance. 20-hydroxy-5,8,11,14-eicosatetraenoic acid cytochrome P450 family 4 subfamily F member 2 Homo sapiens
2 The CYP4A11 F434S and CYP4F2 V433M polymorphisms reduce 20-hydroxyeicosatetraenoic acid production in vitro. 20-hydroxy-5,8,11,14-eicosatetraenoic acid cytochrome P450 family 4 subfamily F member 2 Homo sapiens