Title : Membrane composition modulates prestin-associated charge movement.

Pub. Date : 2008 Aug 15

PMID : 18567583






3 Functional Relationships(s)
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1 We have previously shown that membrane cholesterol modulates the peak voltage of prestin-associated nonlinear capacitance in vivo and in vitro. Cholesterol solute carrier family 26 member 5 Homo sapiens
2 The present study explores the effects of membrane cholesterol and docosahexaenoic acid content on the peak and magnitude of prestin-associated charge movement in a human embryonic kidney (HEK 293) cell model. Cholesterol solute carrier family 26 member 5 Homo sapiens
3 Our results quantify the relation between membrane cholesterol concentration and prestin-associated charge movement and enhance our understanding of how membrane composition modulates prestin function. Cholesterol solute carrier family 26 member 5 Homo sapiens