Title : Reactivation of DFP- and paraoxon-inhibited acetylcholinesterases by pyridinium oximes.

Pub. Date : 2008 Sep 25

PMID : 18565503






2 Functional Relationships(s)
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1 Exposure to the organophosphorus nerve agents such as sarin, soman, cyclosarin, and VX causes acute intoxication by inhibiting acetylcholinesterase (AChE), where the serine residue of the active site can attack the phosphorous atom of the organophosphorus agents to form a strong P-O bond. Serine acetylcholinesterase (Cartwright blood group) Homo sapiens
2 Exposure to the organophosphorus nerve agents such as sarin, soman, cyclosarin, and VX causes acute intoxication by inhibiting acetylcholinesterase (AChE), where the serine residue of the active site can attack the phosphorous atom of the organophosphorus agents to form a strong P-O bond. Serine acetylcholinesterase (Cartwright blood group) Homo sapiens