Title : Protective effects of antithrombin on puromycin aminonucleoside nephrosis in rats.

Pub. Date : 2008 Jul 28

PMID : 18541230






3 Functional Relationships(s)
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1 We investigated the effects of antithrombin, a plasma inhibitor of coagulation factors, in rats with puromycin aminonucleoside-induced nephrosis, which is an experimental model of human nephrotic syndrome. Puromycin Aminonucleoside serpin family C member 1 Homo sapiens
2 Treatment with antithrombin attenuated the puromycin aminonucleoside-induced hematological abnormalities. Puromycin Aminonucleoside serpin family C member 1 Homo sapiens
3 In addition, antithrombin treatment markedly suppressed puromycin aminonucleoside-induced apoptosis of renal tubular epithelial cells. Puromycin Aminonucleoside serpin family C member 1 Homo sapiens