Pub. Date : 2008 Jun 1
PMID : 18519703
2 Functional Relationships(s)Download |
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Sentence | Compound Name | Protein Name | Organism |
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1 | Guggulsterone, a farnesoid X receptor antagonist, inhibits constitutive and inducible STAT3 activation through induction of a protein tyrosine phosphatase SHP-1. | pregna-4,17-diene-3,16-dione | protein tyrosine phosphatase non-receptor type 6 | Homo sapiens | ||
2 | Indeed, we found that GS induced the expression of both the protein and mRNA for tyrosine protein phosphatase SHP-1 that was not due to demethylation of the SHP-1 promoter previously implicated in the epigenetic silencing of SHP-1. | pregna-4,17-diene-3,16-dione | protein tyrosine phosphatase non-receptor type 6 | Homo sapiens |