Pub. Date : 2008 Sep-Oct
PMID : 18519167
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Lipocalin 2 (Lcn2), a mammalian protein that is expressed and secreted in various pathologic states, binds siderophores, which are high-affinity iron chelators. | Iron | lipocalin 2 | Homo sapiens |
| 2 | Lipocalin 2 (Lcn2), a mammalian protein that is expressed and secreted in various pathologic states, binds siderophores, which are high-affinity iron chelators. | Iron | lipocalin 2 | Homo sapiens |
| 3 | Besides its role in limiting iron availability to pathogens in the setting of bacterial infection, Lcn2:siderophore complexes can also deliver iron to cells. | Iron | lipocalin 2 | Homo sapiens |
| 4 | Besides its role in limiting iron availability to pathogens in the setting of bacterial infection, Lcn2:siderophore complexes can also deliver iron to cells. | Iron | lipocalin 2 | Homo sapiens |
| 5 | Anemia induced by phlebotomy, iron deprivation, or phenylhydrazine treatment was associated with upregulation of Lcn2 gene expression in the liver and elevation of serum Lcn2 protein levels. | Iron | lipocalin 2 | Homo sapiens |
| 6 | Anemia induced by phlebotomy, iron deprivation, or phenylhydrazine treatment was associated with upregulation of Lcn2 gene expression in the liver and elevation of serum Lcn2 protein levels. | Iron | lipocalin 2 | Homo sapiens |
| 7 | The upregulation of Lcn2 levels by anemia and hypoxia, which is not directly mediated by iron or erythropoietin, suggests a possible physiological role for Lcn2 during increased iron utilization and mobilization from stores. | Iron | lipocalin 2 | Homo sapiens |
| 8 | The upregulation of Lcn2 levels by anemia and hypoxia, which is not directly mediated by iron or erythropoietin, suggests a possible physiological role for Lcn2 during increased iron utilization and mobilization from stores. | Iron | lipocalin 2 | Homo sapiens |