Title : Ceramide is a cardiotoxin in lipotoxic cardiomyopathy.

Pub. Date : 2008 Oct

PMID : 18515784






1 Functional Relationships(s)
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1 Inhibition of SPT, a rate-limiting enzyme in ceramide biosynthesis, reduced fatty acid and increased glucose oxidation in isolated perfused LpL(GPI) hearts, improved systolic function, and prolonged survival rates. Glucose alanine--glyoxylate and serine--pyruvate aminotransferase Homo sapiens