Title : Kotomolide A arrests cell cycle progression and induces apoptosis through the induction of ATM/p53 and the initiation of mitochondrial system in human non-small cell lung cancer A549 cells.

Pub. Date : 2008 Jul

PMID : 18511169






1 Functional Relationships(s)
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Protein Name
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1 Specific ATM inhibitor, caffeine, significantly decreased KTA-mediated G2/M arrest by inhibiting the phosphorylation of p53 (Serine15) and Chk2. Caffeine tumor protein p53 Homo sapiens