Title : Ydc1p ceramidase triggers organelle fragmentation, apoptosis and accelerated ageing in yeast.

Pub. Date : 2008 Jun

PMID : 18500447






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Saccharomyces cerevisiae dihydroceramidase Ydc1p hydrolyzes ceramide, resulting in accumulation of free long-chain bases and their phosphates. Ceramides alkaline dihydroceramidase Saccharomyces cerevisiae S288C
2 Exogenous addition of ceramide to YDC1-overexpressing cultures increased chronological lifespan and restored organelle function. Ceramides alkaline dihydroceramidase Saccharomyces cerevisiae S288C