Title : Proteomic analysis of phospholipidosis in citalopram treated U937 cells--support for the cholesterol biosynthesis hypothesis.

Pub. Date : 2008 Aug

PMID : 18499393






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Up-regulated proteins were Glyoxalase-I (Glo 1) and 3-Hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (HMGCS1) in cells with PL shown by TEM (favouring the cholesterol biosynthesis increase hypothesis for citalopram induced PL). Cholesterol 3-hydroxy-3-methylglutaryl-CoA synthase 1 Homo sapiens
2 Up-regulated proteins were Glyoxalase-I (Glo 1) and 3-Hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (HMGCS1) in cells with PL shown by TEM (favouring the cholesterol biosynthesis increase hypothesis for citalopram induced PL). Cholesterol 3-hydroxy-3-methylglutaryl-CoA synthase 1 Homo sapiens