Pub. Date : 2008 May 15
PMID : 18483373
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Tamoxifen and aromatase inhibitors differentially affect vascular endothelial growth factor and endostatin levels in women with breast cancer. | Tamoxifen | vascular endothelial growth factor A | Homo sapiens |
| 2 | RESULTS: Tamoxifen therapy resulted in an increase in platelet releasate concentrations of VEGF (P = 0.01) but no change in plasma VEGF. | Tamoxifen | vascular endothelial growth factor A | Homo sapiens |
| 3 | In univariate analysis, aspirin use attenuated the tamoxifen-associated increase in VEGF in the platelet releasate and decreased serum levels of VEGF (P = 0.03). | Tamoxifen | vascular endothelial growth factor A | Homo sapiens |
| 4 | CONCLUSIONS: Tamoxifen and aromatase inhibitor therapy affect VEGF and endostatin levels and likely contribute to the angiogenic balance in breast cancer patients. | Tamoxifen | vascular endothelial growth factor A | Homo sapiens |