Title : p53 expression in concurrent chemoradiotherapy with docetaxel for head and neck squamous cell carcinoma.

Pub. Date : 2009 Feb

PMID : 18472237






3 Functional Relationships(s)
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1 p53 expression in concurrent chemoradiotherapy with docetaxel for head and neck squamous cell carcinoma. Docetaxel tumor protein p53 Homo sapiens
2 BACKGROUND: The current study aimed to evaluate the significance of an immunohistochemical assessment of tumor suppressor p53 as a prognostic marker in head and neck squamous cell carcinoma (HNSCC) patients treated with docetaxel and radiotherapy. Docetaxel tumor protein p53 Homo sapiens
3 METHODS: The expression of tumor suppressor p53 and its phosphorylated form at the Ser392 residue was retrospectively evaluated by immunohistochemistry in 51 Stage T1-3N0-2M0 (except T1N0 glottis) HNSCC patients who were treated with 10mg/m(2)/week docetaxel four to six times and received concurrent chemoradiotherapy. Docetaxel tumor protein p53 Homo sapiens