Title : Cardioprotective effect of vanadyl sulfate on ischemia/reperfusion-induced injury in rat heart in vivo is mediated by activation of protein kinase B and induction of FLICE-inhibitory protein.

Pub. Date : 2008 Spring

PMID : 18466417






2 Functional Relationships(s)
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1 Furthermore, treatment with vanadyl sulfate significantly increased FLICE-inhibitory protein (FLIP) expression, and decreased expression of Fas ligand and Bim in cardiomyocytes. vanadyl sulfate Fas ligand Rattus norvegicus
2 Taken together, rescue of cardiomyocytes by posttreatment with vanadyl sulfate from MI/R injury was mediated by increased FLIP expression and decreased Fas ligand and Bim expression via activation of Akt. vanadyl sulfate Fas ligand Rattus norvegicus