Pub. Date : 1991 Feb
PMID : 1846577
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | To delineate the role of carbohydrate moiety in the expression of in vitro thyrotropic activity of hCG, its variants that lacked sialic acid residues or the entire carbohydrate moiety on one or both subunits were prepared. | Carbohydrates | chorionic gonadotropin subunit beta 5 | Homo sapiens |
2 | Results of these studies strongly suggest that the optimal expression of in vitro thyrotropic activity of hCG variants in FRTL-5 cells may require an alpha-subunit, with intact carbohydrate, in combination with the deglycosylated beta-subunit. | Carbohydrates | chorionic gonadotropin subunit beta 5 | Homo sapiens |
3 | Further, they demonstrate that modification of the hCG carbohydrate moiety alone can transform it from a weak agonist to a potent stimulator of in vitro thyrotropic bioactivity. | Carbohydrates | chorionic gonadotropin subunit beta 5 | Homo sapiens |