Title : Decreased expression of endometrial vessel AQP1 and endometrial epithelium AQP2 related to anovulatory uterine bleeding in premenopausal women.

Pub. Date : 2008 Jul-Aug

PMID : 18463544






3 Functional Relationships(s)
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1 The expression levels of AQP1 and AQP2 mRNA and protein were higher in the secretory phase than those in the proliferative phase (P < 0.01) in normal endometrium, and their expression was related to serum steroid hormones (P < 0.01). Steroids aquaporin 2 Homo sapiens
2 CONCLUSIONS: Our findings indicate that cyclic expression of endometrial AQP1/AQP2 correlated with steroid hormone levels may be essential to normal endometrial function and decreased AQP1/AQP2 expression in endometrial vessels or epithelium may be involved in the occurrence of anovulatory uterine bleeding. Steroids aquaporin 2 Homo sapiens
3 CONCLUSIONS: Our findings indicate that cyclic expression of endometrial AQP1/AQP2 correlated with steroid hormone levels may be essential to normal endometrial function and decreased AQP1/AQP2 expression in endometrial vessels or epithelium may be involved in the occurrence of anovulatory uterine bleeding. Steroids aquaporin 2 Homo sapiens