Title : Expression of alpha-AR subtypes in T lymphocytes and role of the alpha-ARs in mediating modulation of T cell function.

Pub. Date : 2007

PMID : 18463421






2 Functional Relationships(s)
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1 The inhibited lymphocyte proliferation and IFN-gamma and IL-4 production by clonidine were blocked by yohimbine, an alpha(2)-AR antagonist. Clonidine interleukin 4 Rattus norvegicus
2 Either phospholipase C inhibitor U-73122 or protein kinase C inhibitor chelerythrine partially prevented the suppressive effect of clonidine on Con A-stimulated lymphocyte proliferation and IL-4 production. Clonidine interleukin 4 Rattus norvegicus