Title : Metabolite profiling in human urine by LC-MS/MS: method optimization and application for glucuronides from dextromethorphan metabolism.

Pub. Date : 2008 Aug 15

PMID : 18458004






1 Functional Relationships(s)
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1 Our results show that an optimized procedure not only identified the known DEX metabolites as predictors of CYP2D6-specific metabolic pathways but also indicated the presence of additional, so far unknown path-specific glucuronide metabolites. Dextromethorphan cytochrome P450 family 2 subfamily D member 6 Homo sapiens