Title : Molecular architecture of Galphao and the structural basis for RGS16-mediated deactivation.

Pub. Date : 2008 Apr 29

PMID : 18434540






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 To mitigate excessive effector engagement and concomitant signal transmission, the Galpha subunit"s intrinsic activation timer (the rate of GTP hydrolysis) is regulated spatially and temporally by a class of GTPase accelerating proteins (GAPs) known as the regulator of G protein signaling (RGS) family. Guanosine Triphosphate paired like homeodomain 2 Homo sapiens
2 To mitigate excessive effector engagement and concomitant signal transmission, the Galpha subunit"s intrinsic activation timer (the rate of GTP hydrolysis) is regulated spatially and temporally by a class of GTPase accelerating proteins (GAPs) known as the regulator of G protein signaling (RGS) family. Guanosine Triphosphate paired like homeodomain 2 Homo sapiens