Pub. Date : 2008 May
PMID : 18425390
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Alterations of the K-ras and p53 genes in Tamoxifen-associated endometrial carcinoma. | Tamoxifen | tumor protein p53 | Homo sapiens |
| 2 | The median duration of TAM exposure was significantly longer in patients with p53 mutations than those without p53 mutations (62 vs. 30 months, p=0.028). | Tamoxifen | tumor protein p53 | Homo sapiens |
| 3 | The median duration of TAM exposure was significantly longer in patients with p53 mutations than those without p53 mutations (62 vs. 30 months, p=0.028). | Tamoxifen | tumor protein p53 | Homo sapiens |
| 4 | Our observation suggests that prolonged TAM exposure may directly inactivate the p53 gene by acting as a mutagen in a significant fraction of TAM-associated endometrial carcinomas. | Tamoxifen | tumor protein p53 | Homo sapiens |
| 5 | Our observation suggests that prolonged TAM exposure may directly inactivate the p53 gene by acting as a mutagen in a significant fraction of TAM-associated endometrial carcinomas. | Tamoxifen | tumor protein p53 | Homo sapiens |