Title : CDK1 inhibitors antagonize the immediate apoptosis triggered by spindle disruption but promote apoptosis following the subsequent rereplication and abnormal mitosis.

Pub. Date : 2008 May 15

PMID : 18418077






1 Functional Relationships(s)
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1 The massive apoptosis triggered by nocodazole treatment requires the continuous activation of cyclin B1-CDK1 and is antagonized by premature mitotic slippage. Nocodazole cyclin B1 Homo sapiens